Temple University
Philadelphia, PA
B.S. in Biology, Minor in Chemistry | GPA: 3.485 / 4.0. Strong foundation in biochemistry, molecular biology, and organic chemistry.
About Me
Dedicated to advancing targeted cancer immunotherapies through molecular cell biology engineering and computational data science.
Scientific Profile
Hi, I'm Kamari Smalls — a Cancer Immunotherapy & Molecular Biology Researcher
I specialize in adoptive T cell therapy, TCR expression platform optimization, CRISPR/Cas9 genome editing, therapeutic antibody discovery, and computational biology data analysis.
Currently serving as a Researcher in T Cell Immunology & Oncology at Tmunity Therapeutics, Inc. in Philadelphia, PA, I develop novel TCR expression platforms in primary human CD4+ and CD8+ T cells, optimize T cell expansion protocols, and utilize computational biology pipelines to analyze dextramer binding. Previously at Integral Molecular, Inc., I supported therapeutic antibody discovery targeting membrane proteins using Membrane Proteome Array (MPA) technology and co-authored NIH-grant-funded scientific reports.
I hold a Master of Science in Molecular & Cell Biology and Genetics from Drexel University College of Medicine and a B.S. in Biology (Minor in Chemistry) from Temple University, along with specialized certification in Bioinformatics with R and Data Products.
T Cell Engineering
TCR expression platforms, lentiviral vectors, and primary human T cell modification.
CRISPR/Cas9 & Genetics
Targeted gene knockout and editing in CD4+ / CD8+ immune cells.
Bioinformatics (Python/R)
Computational analysis, flow cytometry data processing, and protein structure modeling.
Antibody Discovery
Membrane Proteome Array characterization and therapeutic target identification.
Academic & Professional Journey
Integral Molecular, Inc.
Philadelphia, PA
Laboratory Research Assistant in Antibody Discovery. Characterized therapeutic antibodies using Membrane Proteome Array technology.
Drexel University
College of Medicine
M.S. in Molecular & Cell Biology and Genetics. Advanced research in tumor biology, medical genetics, and computational genomics.
Tmunity Therapeutics
Philadelphia, PA
Researcher in T Cell Immunology & Oncology. Engineering TCR platforms and CRISPR/Cas9 systems in human primary T cells.
"Bridging cutting-edge molecular engineering and computational data analysis to accelerate personalized adoptive cell therapies for cancer patients."
Technical Expertise
Core laboratory and bioinformatic skills honed through industrial biotechnology research and rigorous graduate studies.
TCR Platform & CRISPR/Cas9
Primary T cell engineering, lentiviral transduction, and gene editing.
95%Flow Cytometry & Dextramers
Multi-color flow cytometry, TCR-dextramer binding, and cell phenotyping.
92%Bioinformatics (Python & R)
Computational biology pipelines, data products, and structural modeling.
90%Primary Specimen Processing
Tumor tissue processing, CD4+/CD8+ T cell isolations, and aseptic culture.
94%Membrane Proteome Arrays
High-throughput antibody discovery targeting membrane protein targets.
92%Molecular Assays (PCR/Western)
qPCR, dPCR, ELISA, Western Blotting, DNA preps, transformation.
96%+
Years Research Experience
Biotech Research Roles
Advanced Academic Degrees
+
Core Lab & Computational Tools